Hexamethonium Bromide NEW
| Price | $29 |
| Package | 1mL |
| Supply Ability: | 10g |
| Update Time: | 2026-05-29 |
Product Details
| Product Name: Hexamethonium Bromide | CAS No.: 55-97-0 |
| Purity: 99.95% | Supply Ability: 10g |
| Release date: 2026/05/29 |
Product Introduction
Bioactivity
| Name | Hexamethonium Bromide |
| Description | Hexamethonium Bromide (Hexamethonium Dibromide), a specific antagonist of neuronal-type nicotinic AChR in ganglia, is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. |
| In vitro | Hexamethonium Bromide is effective against Ach and carbachol (CCh) on the amplitude of endplate responses of rat omohyoid muscle with EC50 of 300 μM and 100 μM, respectively. Hexamethonium Bromide (50-200 μM) causes an increase in the amplitude of nerve-evoked endplate currents (e.p.cs) recorded in the presence of 0.6 μM tubocurarine. Hexamethonium Bromide is also a weak inhibitor of acetylcholinesterase activity in rat muscle homogenates with EC50 of 1.5 mM. [1] Hexamethonium Bromide (200 μM) decreases the time constant of decay of both endplate currents (e.p.cs) (by ~25%) and miniature endplate currents (m.e.p.cs) (by ~20%) in the rat hemi-diaphragm muscle. At low frequencies of stimulation (0.5-2 Hz), Hexamethonium Bromide (200 μM) increases e.p.c. quantal content by 30-40%. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.76 mM), Sonication is recommended. DMSO : 9 mg/mL (24.85 mM), Sonication is recommended. H2O : 250 mg/mL (690.25 mM), Sonication is recommended. |
| Keywords | sympathetic | spontaneously. hypertensive | Nicotinic acetylcholine receptors | nAChR | mAChR | Inhibitor | inhibit | hypertension | Hexamethonium Bromide | Hexamethonium | DopamineReceptor | Dopamine Receptor | Dopamine | Apoptosis | activity |
| Inhibitors Related | Stavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | N,N-Dicyclohexylcarbodiimide | Dimethyl phthalate | Alginic acid | Sildenafil citrate |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $29.00 |
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-05-29 | |
| $29.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-05-29 | |
| $6.00 |
Chemwill Asia Co.,Ltd.
|
2020-06-02 | ||
|
VIP7Y
|
Shaanxi Dideu Medichem Co. Ltd
|
2020-05-10 | ||
| $9.80 |
VIP7Y
|
Career Henan Chemical Co
|
2020-01-13 | |
| $29.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-05-02 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY