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Postion:Product Catalog >HPN-01
HPN-01
  • HPN-01

HPN-01 NEW

Price $88
Package 2mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: HPN-01 CAS No.: 928655-63-4
Purity: 98.17% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameHPN-01
DescriptionHPN-01 (IKK inhibitor XII) is a selective IKK inhibitor that inhibits IKK-α, IKK-β, and IKK-ε. HPN-01 reduces the severity of the disease, attenuates the immune imbalance, and prolongs the lifespan of mice in a model of autoimmune encephalomyelitis, and can be used to study immune disorders.
In vitroHPN-01 could inhibit the expression of SREBP-1 and SREBP-2 in human primary hepatocytes, and the IC50 values were 1.71 and 3.43, respectively. It is commonly used in the study of nonalcoholic fatty liver disease (NAFLD)[1].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (8.21 mM), Sonication is recommended.
DMSO : 80 mg/mL (199.07 mM), Sonication is recommended.
KeywordsIκB | IKK-ε | IKK-β | IKK-α | IKK | IkB/IKK | IkB | HPN-01
Inhibitors RelatedAmlexanox | Malachite green oxalate | MRT 67307 dihydrochloride | Rosmarinic acid | Abietic Acid | Peramivir Trihydrate | Resveratrol | GSK8612 | CCCP | Allicin | Vinpocetine | Dehydrocostus Lactone
Related Compound LibrariesNF-κB Signaling Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Drug Repurposing Compound Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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