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Postion:Product Catalog >HQ461
HQ461
  • HQ461

HQ461 NEW

Price $38 $54 $89
Package 1mg 2mg 5mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: HQ461 CAS No.: 1226443-41-9
Purity: 98.11% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NameHQ461
DescriptionHQ461 is a molecular glue that promotes CDK12-DDB1 interaction, triggering cyclin K degradation, decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 62 mg/mL (179.48 mM), Sonication and heating to 60℃ are recommended.
KeywordsMolecularGlues | Molecular Glues | molecular glue | Inhibitor | inhibit | HQ-461 | HQ461 | HQ 461 | DNA damage | cyclin K degrader | Cyclin dependent kinase | CDK12 substrate phosphorylation | CDK12 | CDK
Inhibitors RelatedRibociclib | Amantadine | 2-Chloropyrazine | Kojic acid | PT-179 | Abemaciclib | Thalidomide | 2,4,6-Trihydroxybenzoic acid | Lenalidomide | Palbociclib | Abemaciclib methanesulfonate | Sodium Oxamate
Related Compound LibrariesBioactive Compound Library | Kinase Inhibitor Library | Post-Translational Modification Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library | High-Efficiency Gene Editing Small Molecule Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Anhui Ruihan Technology Co., Ltd
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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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