Hygromycin B NEW
| Price | $48 | $70 |
| Package | 200mg | 500mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-17 |
Product Details
| Product Name: Hygromycin B | CAS No.: 31282-04-9 |
| Purity: 99.95% | Supply Ability: 10g |
| Release date: 2026/07/17 |
Product Introduction
Bioactivity
| Name | Hygromycin B |
| Description | Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis in both prokaryotic and eukaryotic cells by interfering with translocation and causing mistranslation by the 70S ribosome. It is commonly used for the selection of cells transfected with the hph or hyg resistance gene. |
| In vitro | METHODS: Mouse PDAC cells 14387T were transfected with lentiCRISPRv2 hygro lentivirus, and after 48 h, the transfected cells were cultured in new medium containing Hygromycin B (500 μg/mL) for two weeks, and the successful transfected cells were screened. RESULTS: Hygromycin B screened the lentivirally successfully transfected cells. [1] METHODS: E. coli was cultured in medium containing Hygromycin B (0-8 μg/mL) and cell growth was monitored using a Klett-Summerson colorimeter. RESULTS: Hygromycin B reduced the number of viable cells and increased doubling time in a concentration-dependent manner.Hygromycin B inhibited the number of viable cells by 50% at a concentration of 20 μg/mL, and halved the rate of growth at a concentration of 25 μg/mL. [2] |
| In vivo | METHODS: To assay antiviral activity in vivo, Hygromycin B (0-5 μmoL/kg) was administered intraperitoneally to MHV-A59-infected BALB/c mice twice daily for three days. RESULTS: Hygromycin B was able to reduce the levels of viral replication and necrotic liver foci in vivo. [3] |
| Storage | Keep away from moisture Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 240 mg/mL (454.96 mM), Sonication is recommended. H2O : 125 mg/mL (236.96 mM), Sonication is recommended. 5% DMSO+95% Saline : 1.58 mg/mL (3 mM), Solution. Saline : 50 mg/mL (94.78 mM), Solution. 10% DMSO+90% Saline : 3 mg/mL (5.69 mM), Solution. |
| Keywords | Inhibitor | inhibit | Hygromycin B | Fungal | Bacterial | Antibiotic | 70S ribosome |
| Inhibitors Related | Neomycin sulfate | Calcium Propionate | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Benzyl propionate | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate |
| Related Compound Libraries | Anti-Parasitic Compound Library | Bioactive Compound Library | Anti-Fungal Compound Library | Drug Repurposing Compound Library | Saccharide and Glycoside Natural Product Library | Natural Product Library | Antiparasitic Natural Product Library | Microbial Natural Product Library | Inhibitor Library | Anti-infective Natural Product Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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