Hyperforin NEW
| Price | $400 |
| Package | 1mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Hyperforin | CAS No.: 11079-53-1 |
| Purity: 90.00% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Hyperforin |
| Description | Hyperforin, a natural product from Hypericum, is commonly used as an antidepressant and also has neurological, inflammatory, antimicrobial, antitumor and antiangiogenic effects. Hyperforin acts as a monoamine reuptake inhibitor (MRI) in vitro, including serotonin, norepinephrine, dopamine, GABA, and glutamate, with an IC 50 of ≈0.1 μg/mL. Hyperforin is also capable of inducing the cytochrome P450 enzymes, CYP3A4 and CYP2C9, through binding to and activation of the?pregnane X receptor. Hyperforin is capable of activating TRPC6 channels by binding to a specific motif. |
| In vitro | Methods: Hyperforin (0.1, 1, 10 μM) was used to treat TNF α-stimulated HaCaT cells, and the expression of related proteins was determined by Western Blot. Results: Hyperforin at a dose of 10 μM reduced the expression of p-p38, p-ERK, p-JNK, and p-STAT3 in HaCaT cells. [3] |
| In vivo | Methods: Hyperforin (5 mg/kg, once a day, 7 days) was used to treat IMQ-induced psoriasis-like mouse models to observe whether it improved the skin lesions of psoriasis. Results: Hyperforin significantly improved skin lesions throughout the treatment period, while inhibiting the infiltration of CD3+ T cells and downregulating the expression of Il1, Il6, Il23, Il17a, Il22, and antimicrobial peptides (AMPs) in skin lesions. [3] |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Hyperforin | COX-1 | 5HTReceptor | 5HT Receptor | 5-HT |
| Inhibitors Related | Quadrol | Rosiglitazone | 2,4,6-Tri-tert-butylphenol | Caffeic Acid | Chlorocresol | L-Ascorbic acid | Probenecid | trans-Cinnamaldehyde | L-Ascorbic acid sodium salt | 2-Nitrobenzoic acid | Magnesium Chloride Hexahydrate | Magnesium sulfate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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