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Postion:Product Catalog >API>Hormones and the Endocrine System>Prostaglandin drugs>Iloprost
Iloprost
  • Iloprost

Iloprost NEW

Price $855 $3650
Package 1mg 5mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Iloprost CAS No.: 78919-13-8
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

NameIloprost
DescriptionIloprost (Ciloprost) is a stabilized synthetic analog of prostaglandin I2, an inhibitor of platelet aggregation and vasodilation, used in the study of cardiovascular disease.
In vitroIloprost is a PGI2 analog that affects the maturation and developmental competence of bovine oocytes. 0.5 μM Iloprost treatment for 22-24 hours increased the blastocyst rate and the proportion of expanded blastocysts in bovine embryos, increased the maturation rate of bovine oocytes and the rate of cumulus expansion, and increased mRNA expression of genes associated with cumulus expansion. [1] Iloprost reduces the occurrence of apoptosis in COC cells and promotes an anti-apoptotic balance in the transcription of apoptosis-related genes (BAX and BCL2). [1]
In vivo0.3 mg/kg/min Iloprost, administered intravenously by minipump for 33 days, showed significant anti-metastatic activity in a rat model of spontaneous metastatic tumors.[3] 0.2 mg/kg/day Iloprost, administered intravenously for 10 days, attenuated the effects of hyperoxia and reduced inflammation in the lungs of neonatal mice, where cyclooxygenase-2 (COX-2/PTGS2) mediated hyperoxia-induced injury.[2]
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 80 mg/mL (221.92 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween-80+45% Saline : 3.3 mg/mL (9.15 mM), Sonication is recommended.
KeywordsZK-36374 | ProstaglandinReceptor | Prostaglandin Receptor | Iloprost | EndogenousMetabolite | Endogenous Metabolite
Inhibitors RelatedSucrose | Aceglutamide | Nicotinamide riboside malate | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Formamide | Glycerol | Thymidine | Corn starch | Gluconate Calcium | DL-Lysine

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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