Inarigivir NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-22 |
Product Details
| Product Name: Inarigivir | CAS No.: 475650-36-3 |
| Supply Ability: 10g | Release date: 2026/04/22 |
Product Introduction
Bioactivity
| Name | Inarigivir |
| Description | Inarigivir (ORI-9020) is a dinucleotide that significantly reduces liver HBV DNA. |
| Animal Research | For the first animal experiment, Inarigivir is prepared fresh daily at a dosage of 100 mg/kg of body weight /day, which is equal to 170 mol/kg/day and is injected intraperitoneally (i.p.) using cremaphor-ethanol-saline (CES) (10:10:80) or physiological saline as vehicles. ADV, the positive control, is prepared using the CES vehicle. A dosage of 10 mg/kg/day (19.9 mol/kg/day) is used. In the second experiment to determine the minimal effective concentration, Inarigivir is prepared in sterile saline in onehalf-log dilutions from 50 to 0.05 mg/kg/day. The drug is delivered i.p. in a volume of 0.1 ml. Liver samples are analyzed for HBV DNA, HBV RNA, and HBcAg, and serum samples are processed for HBV DNA, HBeAg, and HBsAg. |
| In vitro | Inarigivir (100 mg/kg/day, I.p.) significantly reduces viral DNA in the liver and shows anti-HBV activity similar to ADV positive control. Inarigivir does not affect levels of HBV RNA in the liver, levels of HBeAg in serum, or mean titers of HBsAg. The minimal effective dose is identified to be between 1.6 and 0.5 mg/kg/day using liver HBV DNA values. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | DMSO : Soluble |
| Keywords | SB9000 | SB 9000 | ORI9020 | ORI 9020 | Inarigivir | HBV |
| Inhibitors Related | Doxorubicin hydrochloride | Famciclovir | Lamivudine | Cetylpyridinium Chloride | Tenofovir Disoproxil Fumarate | Estradiol benzoate | Thiamine hydrochloride | (Tetrahydro-2H-pyran-4-yl)methanol | Adefovir | 4-Hydroxyacetophenone | Nicotinamide | Tenofovir |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $52.00 |
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-07-15 | |
|
VIP2Y
|
Shaanxi Dideu New Materials Co. Ltd
|
2026-07-08 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY