Integrin-IN-2 NEW
| Price | $1520 |
| Package | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2025-07-17 |
Product Details
| Product Name: Integrin-IN-2 | CAS No.: 2378617-67-3 |
| Supply Ability: 10g | Release date: 2025/07/17 |
Product Introduction
Bioactivity
| Name | Integrin-IN-2 |
| Description | Integrin-IN-2 is an orally bioavailable pan αv integrin inhibitor.Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively. |
| In vivo | In vivo pharmacokinetic studies conducted on CD rats have demonstrated that the racemic compound Integrin-IN-2 (compound 39) displays a low plasma clearance rate of 8 mL/(min·kg), coupled with a low to moderate distribution volume of 0.5 L/kg. It exhibits a moderate half-life of 1.8 hours and an exceptionally high bioavailability of 98%. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | αvβ8 | αvβ6 | αvβ5 | αvβ3 | Integrin-IN-2 | IntegrinIN2 | Integrin IN 2 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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