Product Details
| Product Name: iopromide | CAS No.: 73334-07-3 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: 200ton/month | Release date: 2026/07/14 |
| Common Name | iopromide | ||
|---|---|---|---|
| CAS Number | 73334-07-3 | Molecular Weight | 791.112 |
| Density | 2.2±0.1 g/cm3 | Boiling Point | 840.9±65.0 °C at 760 mmHg |
| Molecular Formula | C18H24I3N3O8 | Melting Point | broad (160oC transition) |
| MSDS | USA | Flash Point | 462.4±34.3 °C |
Use of iopromide
Iopromide is a water-soluble, non-ionic, monomeric, low-osmolar, iodine-based contrast medium for intravascular administration.
| Name | iopromide |
|---|---|
| Synonym | More Synonyms |
| Description | Iopromide is a water-soluble, non-ionic, monomeric, low-osmolar, iodine-based contrast medium for intravascular administration. |
|---|---|
| Related Catalog | Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease |
| In Vivo | Contrast medium-induced nephropathy can be induced by tail intravenous administration of iopromide[1]. In randomized controlled trials, the global image quality and diagnostic quality with iobitridol does not differ from those with other low-osmolar contrast media (iohexol, iopromide, iopamidol, iomeprol and ioxaglate) or the iso-osmolar contrast medium iodixanol in adults or children undergoing radiographic imaging. Large post-marketing surveillance studies have confirmed that iobitridol produces good or excellent opacification and is an effective contrast agent in the vast majority of patients. Iobitridol is generally well tolerated and had a tolerability profile similar to that of other low-osmolar and iso-osmolar contrast media. Thus, iobitridol is an effective intravascular agent for contrast enhancement in diagnostic imaging[2]. |
| Animal Admin | Mice: Male C57/BL6J mice are randomly divided into 7 groups: control, diabetes mellitus (D), CIN, diabetes mellitus+CIN (DC), diabetes mellitus+Breviscapine (DB), CIN+Breviscapine (CIN+B) and diabetes mellitus+CIN+Breviscapine (DCB). After the model of diabetes mellitus is established, mice are prohibited drinking water for one night, and then mice are injected at a dose of 10 mL/kg iopromide via tail vein administration over the course of 1 minute. Then the mice are treated intragastrically with or without Breviscapine (10 mg/kg/d) for 4 weeks. Other mice groups except for Breviscapine treatment groups (DB, DCB and CIN+B) are administered the same volume of phosphate buffered solution intragastrically for 4 weeks. Then mice are sacrificed by an intraperitoneal injection of chloral hydrate[1]. |
| References | [1]. Jiang W, et al. Breviscapine attenuatted contrast medium-induced nephropathy via PKC/Akt/MAPK signalling in diabetic mice. Am J Transl Res. 2016 Feb 15;8(2):329-41. [2]. McCormack PL, et al. Iobitridol: a review of its use as a contrast medium in diagnostic imaging. Clin Drug Investig. 2013 Feb;33(2):155-66. |
Company Profile Introduction
We are Zhejiang Multinpharma Co., Ltd. and Brother Company named of Hangzhou Multinpharma.com Co.,Ltd and Hongrui TechaCo., Ltd. and .,were established in February and September 2002, respectively. The pilot plant is located in Zhejiang Toumang Economic Development Zone, Linhai City, Taizhou City, Zhejiang Province. Within the committee), R & D and sales deparment are located in Hangzhou.
Both company are science and technology company focusing on scientific research technology, dedicated to pharmaceutical and chemical production technology services, CRO customization, continuous flow microreaction technology services, and providing overall solutions for microreaction equipment... READ MO
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