Product Details
| Product Name:
IP7e |
CAS No.:
500164-74-9 |
| Purity:
99.86% |
Supply Ability:
10g |
| Release date:
2026/07/04 |
Product Introduction
Bioactivity
| Name | IP7e |
| Description | IP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM. |
| In vivo | IP7e(10 mg/kg) attenuates inflammation and neurodegeneration in spinal cords of EAE mice by an NF-kB pathway-dependent process. IP7e preventive treatment reduces the incidence and the severity of an MS murine model, i.e. experimental autoimmune encephalomyelitis (EAE)[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 95 mg/mL (243.32 mM), Sonication is recommended.
|
| Keywords | orally | Nurr1 | NF-kB | IP7e | Inhibitor | inhibit | brain-penetrant |
| Inhibitors Related | Amodiaquine | Cytosporone B | Nurr1 agonist 2 | TMPA | Broussochalcone A | DIM-C-pPhOH | C-DIM12 | Nurr1 agonist 8 | DIM-C-pPhOCH3 | NOT Receptor Modulator 1 | Nurr1 agonist 7 | Nur77 modulator 1 |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Suppliers |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |