Isoescin IB NEW
| Price | $84 | $213 | $347 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Isoescin IB | CAS No.: 219944-46-4 |
| Purity: 99.42% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Isoescin IB |
| Description | Isoescin IB is a natural product from Aesculus hippocastanum L. Isoescin IB and Escin IB are the chief active ingredients in escin. |
| In vivo | Five groups of Wistar rats (n=6 per group) were treated with either an intravenous (IV) dose (2.78mg/kg) of sodium escinate (corresponding to 0.5mg/kg of Escin IB and 0.5mg/kg of Isoescin IB), an IV dose (0.5mg/kg) and an oral dose (4mg/kg) of pure Escin IB or Isoescin IB. The administration of sodium escinate, which contains the two isomers, gave rise to higher terminal phase half-life (t1/2) and mean residence time (MRT) values for both Escin IB and Isoescin IB compared to the corresponding compounds administered alone. The absorption of Escin IB and Isoescin IB was very poor, with the oral bioavailability (F) values of <2% observed for both compounds. The two compounds were found to isomerize in vivo, wherein the conversion of Escin IB to Isoescin IB was much easier than that of Isoescin IB to Escin IB[1]. |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (3.54 mM), Sonication is recommended. DMSO : 100 mg/mL (88.4 mM), Sonication is recommended. |
| Keywords | Isoescin IB | Inhibitor | inhibit | Escin IB | Escin |
| Related Compound Libraries | Terpene Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Natural Product Library | Saccharide and Glycoside Natural Product Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Bioactive Lipid Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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