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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>Istaroxime
Istaroxime
  • Istaroxime

Istaroxime NEW

Price $2220 $2680 $3200
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-21

Product Details

Product Name: Istaroxime CAS No.: 203737-93-3
Supply Ability: 10g Release date: 2026/05/21

Product Introduction

Bioactivity

NameIstaroxime
DescriptionIstaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM).
In vitroIstaroxime inhibits the Na+/K+-ATPase activity from the dog kidney (IC50: 0.43 ± 0.15 μM). Istaroxime acting as a positive inotropic compound through the inhibition of the Na+, K+-ATPase[2]. Inhibition of Na+/K+-ATPase activity in preparations from guinea pig kidney yielded potencies of 8.5 μM for PST2744[3].
In vivoIstaroxime (PST2744) causes a progressive to enhance in +dP/dtmax throughout the infusion. That reaches 80% (ED80) at the cumulative dose of 1.89±0.37 mg/kg and a peak of 140±3.5% at the dose (EDmax) of 4.88±0.6 mg/kg[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsPST-2744 | PST 2744 | Na+,K+-ATPase | Istaroxime
Inhibitors RelatedTirofiban hydrochloride monohydrate | Sodium oleate | Permethrin | Tolbutamide | trans-Aconitic acid | Phlorizin | Chlorpropamide | 2,3-Butanedione 2-Monoxime | Revaprazan hydrochloride | Oleic acid | Cyclocreatine | Esomeprazole Sodium

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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