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Postion:Product Catalog >API>Antiparasitic drugs>Antifilarial and Leishmaniasis Drugs>Ivermectin
Ivermectin
  • Ivermectin

Ivermectin NEW

Price $53
Package 500mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Ivermectin CAS No.: 70288-86-7
Purity: 96.38% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameIvermectin
DescriptionIvermectin (MK-933) is an activator of glutamate-gated chloride channels (GluCls) with antiparasitic activity.
In vitroIvermectin exhibits antiviral activity against HIV-1 and Dengue fever virus. It binds to a novel site on GABAA receptors in hippocampal embryonic neurons of mice, conformationally enhancing the affinity of the GABA binding site. In nematodes, the compound interacts with glutamate-gated chloride channels (GluCls), disrupting the regulation mediated by GluCl activity.
In vivoIntraperitoneal injection of Ivermectin (1.25-10 mg/kg) can reduce the consumption of alcohol and saccharin. For mice exposed to lethal doses of LPS, Ivermectin inhibits LPS-induced NF-kB translocation and enhances survival rates.
StorageKeep away from moisture,Store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationEthanol : 27 mg/mL (30.85 mM), Sonication is recommended.
DMSO : 257.5 mg/mL (294.26 mM), Sonication is recommended.
H2O : < 1 mg/mL (insoluble or slightly soluble)
KeywordsSARS-CoV | SARSCoV | SARS coronavirus | Parasite | P2XReceptor | P2X4 | P2X Receptor | MK933 | MK 933 | Mitophagy | Mitochondrial Autophagy | Ivermectin | Inhibitor | inhibit | Human immunodeficiency virus | HSV | HIVProtease | HIV Protease | HIV | Herpes simplex virus | GluCl channels | Autophagy | Antibiotic
Inhibitors RelatedNeomycin sulfate | Aceglutamide | Hemin | Emtricitabine | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Sulfamethoxazole sodium | Fenpyroximate | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate
Related Compound LibrariesPesticide Compound Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Drug Repurposing Compound Library | Natural Product Library | Anti-Viral Compound Library | Antiparasitic Natural Product Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Anti-infective Natural Product Library | Ion Channel Targeted Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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