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Postion:Product Catalog >Jasplakinolide
Jasplakinolide
  • Jasplakinolide

Jasplakinolide NEW

Price $998
Package 100μg
Supply Ability: 10g
Update Time: 2026-04-20

Product Details

Product Name: Jasplakinolide CAS No.: 102396-24-7
Supply Ability: 10g Release date: 2026/04/20

Product Introduction

Bioactivity

NameJasplakinolide
DescriptionJasplakinolide(Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifungal and antitumor activity and stabilizes pre-existing actin filaments. Jasplakinolide competitively binds to F-actin with the ghost pen cyclic peptide and has a Kd value of 15 nM for F-actin.
In vitroJasplakinolide, at a concentration of 1 mM for 60 minutes, prompts the development of apical extensions rich in actin within fixed Toxoplasma gondii tachyzoites. It exhibits an IC50 of 35 nM against PC3 prostate carcinoma cells, underscoring its potent antiproliferative capability. Additionally, when introduced at 10 μM for 2 hours during mitosis, jasplakinolide leads to the formation of binucleated cells. This compound also triggers the production of F-actin-enriched apical extensions in Toxoplasma gondii tachyzoites, demonstrating its broad impact on cellular architecture.[1][2]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsNSC613009 | NSC 613009 | MicrotubuleAssociated | Microtubule Associated | Jasplakinolide | Fungal | Arp2/3 complex
Inhibitors RelatedCalcium Propionate | Dehydroacetic acid sodium | Potassium gluconate | Flubendazole | D-Gluconic acid (solution) (50% in H2O) | Sulfacetamide sodium | Terbinafine hydrochloride | Benzyl propionate | Sodium formate | Magnesium acetate tetrahydrate | Geraniol | Methylene Blue trihydrate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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