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Postion:Product Catalog >JNJ-1289
JNJ-1289
  • JNJ-1289

JNJ-1289 NEW

Price $83 $217 $306
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: JNJ-1289 CAS No.: 792898-18-1
Purity: 98.16% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameJNJ-1289
DescriptionJNJ-1289 is a selective, potent, and competitive inhibitor of human spermine oxidase (hSMOX) with an IC50 value of 50 nM.JNJ-1289 has potential anticancer and anti-inflammatory activity for the study of polyamine catabolic disorders.
In vitroIn a time-dependent manner, JNJ-1289 inhibits hSMOX activity, with assessments at 0 and 2 hours[1]. Initially, JNJ-1289 forms a weak complex with hSMOX, characterized by an apparent Ki value of 1.4 μM. Subsequently, a relatively slow protein isomerization occurs, leading to the formation of the final tightly bound inhibitor-enzyme complex[1].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+90% Saline : 2.5 mg/mL (8.11 mM), Sonication is recommended.
DMSO : 50 mg/mL (162.15 mM), Sonication is recommended.
KeywordshSmo
Inhibitors RelatedIHR-1 | ALLO-2 | Purmorphamine | LEQ506 | Halcinonide | MRT-83 | BMS-833923 | SAG | Sonidegib | SMO-IN-2 | Jervine | MK-4101
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Wnt/Hedgehog/Notch Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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