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Postion:Product Catalog >JTK-853
JTK-853
  • JTK-853

JTK-853 NEW

Price $4859 $6318 $8219
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: JTK-853 CAS No.: 954389-09-4
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

NameJTK-853
DescriptionJTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase, exhibiting effective antiviral activity in HCV replicon cells with EC50s of 0.38 μM for genotype 1a H77 strain and 0.035 μM for genotype 1b Con1 strain.
In vitroJTK-853 inhibits the drug-resistant colony formation in the genotype 1a replicon cells, and the numbers of JTK-853-resistant colonies are much lower than those of GS-9190-resistant colonies for both genotypes. When JTK-853 is incubated with the replicon cells for 48 h, it shows antiviral activity against genotype 1a H77 and 1b Con1 replicon cells (EC90: 6.5±0.5 and 0.34±0.05 μM, respectively). In 2-week culture, JTK-853(at 10 μM) causes apparent Huh-7.5 cell death[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsJTK-853 | JTK853 | JTK 853 | 1b Con1 HCV | 1a H77 HCV
Inhibitors RelatedEIDD-1931 | Methyl 2-amino-5-bromobenzoate | RO8191 | Sofosbuvir | Deferiprone | Ribavirin | Artemisinin | HCV-IN-29 | Honokiol | Chlorcyclizine | (Tetrahydro-2H-pyran-4-yl)methanol | Resiquimod

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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