L-Ascorbic acid NEW
| Price | $42 |
| Package | 1g |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: L-Ascorbic acid | CAS No.: 50-81-7 |
| Purity: 99.89% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | L-Ascorbic acid |
| Description | L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-Ascorbic acid is used in the treatment of scurvy. |
| In vitro | METHODS: Human osteosarcoma cells MG-63 were treated with L-Ascorbic acid (62.5-1000 μM) for 3-24 h. Cell viability was measured by XTT Assay. RESULTS: Cell viability was consistently >95% when cells were treated with L-Ascorbic acid at concentrations of 0-250 μM. When higher concentrations were used, a dose-dependent decrease in cell viability was observed. [1] METHODS: Melanoma cells WM1366 were treated with L-Ascorbic acid (5-50 μM) for 24 h. The expression levels of target proteins were measured using Western Blot. RESULTS: The lowest concentration of L-Ascorbic acid (5 μM) significantly reduced the normoxic expression of HIF-1α protein in human melanoma cell lines. [2] |
| In vivo | METHODS: L-Ascorbic acid (1-4.5 g/kg) was administered intraperitoneally to irradiated C57BL/6 mice to detect radioprotective activity. RESULTS: Administration of 3 g/kg L-Ascorbic acid immediately after exposure significantly increased the survival rate of mice after 7-8 Gy WBI. However, administration of less than 3 g/kg L-Ascorbic acid was ineffective, and 4 g/kg and above was harmful to mice. [3] METHODS: To investigate the effects on amnesia, L-Ascorbic acid (60-160 mg/kg) was administered intraperitoneally to diazepam, scopolamine, and aging-induced amnesic Swiss mice once daily for 3-8 days. RESULTS: L-Ascorbic acid improved learning and memory in aging mice, as evidenced by decreased transfer latency and increased descending latency. [4] |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 35.7 mg/mL (202.7 mM), Sonication is recommended. DMSO : 60 mg/mL (340.68 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | VC | species | ROS | ReactiveOxygenSpecies | Reactive Oxygen Species | reactive | oxygen | L-Ascorbic acid | LAscorbic acid | L Ascorbic acid | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | Electron | donor | deposition | collagen | channel | Cav3.2 | cancer | CalciumChannel | Calcium Channel | Ca2+ channels | Ca channels | Apoptosis | antioxidant |
| Inhibitors Related | Sucrose | Stavudine | Daidzein | Guanidine hydrochloride | Fumaric acid | Tributyrin | Ferulic Acid | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Neuroprotective Compound Library | Tobacco Monomer Library | Microbial Natural Product Library | Immunology/Inflammation Compound Library | Cosmetic Ingredient Compound Library | Anti-infective Natural Product Library | Anti-Aging Compound Library | Ancient Chinese Classical Formulas Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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