L-Glutamine NEW
| Price | $50 |
| Package | 1mL |
| Supply Ability: | 10g |
| Update Time: | 2026-05-15 |
Product Details
| Product Name: L-Glutamine | CAS No.: 56-85-9 |
| Purity: 99.66% | Supply Ability: 10g |
| Release date: 2026/05/15 |
Product Introduction
Bioactivity
| Name | L-Glutamine |
| Description | L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid abundantly present in the human body and involved in numerous metabolic processes. It serves multiple functions as a nitrogen source donor, energy substrate, and antioxidant precursor. It can be used in cell biology, immunology, and oncology research. |
| In vitro | Methods: L-glutamine (0.5, 1.0, 2.0, 10.0 mM) was added to male SD rat thoracic aortic vascular rings (with endothelium) (pre-contracted with 1 μM phenylephrine), and tension changes were recorded in real time. Results: 0.5 mM L-Glutamine increased relaxation velocity by 93%. De-endothelialization or L-NAME pretreatment attenuated the relaxation response by approximately 70–80%. L-Glutamine increased tissue cGMP levels by 77%. [1] Methods: Primary knee cartilage cells from 3-week-old SD rats were treated with L-glutamine (0, 5, 10, 20 mM). Some groups were pretreated with IL-1β (10 ng/mL) for 2 hours before L-glutamine treatment for 24 or 48 hours. Cell viability was assessed using the CCK-8 assay. Results: IL-1β reduced cell viability, while L-Glutamine concentration-dependently reversed this effect, with the most pronounced effect observed at 20 mM. [2] |
| In vivo | Methods: Female BALB/c mice received a single intraperitoneal injection of cantharidin (CTD) (2 mg/kg) or oral administration of L-glutamine (Gln) (1 or 2 g/kg). Four hours post-treatment, hearts were subjected to hematoxylin and eosin (HE) staining, and microscopic examination was performed to assess pathological changes such as inflammation and congestion. Results: The CTD group exhibited inflammatory cell infiltration and myocardial interstitial congestion in the heart; the L-Glutamine pretreatment group showed significantly reduced myocardial inflammation and pathological alterations. [3] Methods: Male C57BL/6J mice received intraperitoneal injections of L-glutamine (Gln) (50 mg/kg). Thirty minutes later, LPS (10 μg/kg) + D-Gal (700 mg/kg) was administered intraperitoneally to induce fulminant hepatitis. Animals were euthanized 6 hours after LPS/D-Gal injection.Plasma samples were collected to measure ALT and AST activity; liver tissue was examined histopathologically via HE staining. Results: L-Glutamine pretreatment significantly reduced LPS/D-Gal-induced elevations in plasma ALT and AST levels and mitigated histopathological liver damage (disorganized hepatic lobule architecture, hepatocyte necrosis, inflammatory cell infiltration).[4] |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : Insoluble H2O : 40.7 mg/mL (278.5 mM), Sonication and heating are recommended. |
| Keywords | mGluR | Metabotropic glutamate receptors | L-Glutamine | LGlutamine | L-Glutamic acid | L Glutamine | Inhibitor | inhibit | Ferroptosis | EndogenousMetabolite | Endogenous Metabolite |
| Inhibitors Related | Sucrose | Aceglutamide | Hemin | Nicotinamide riboside malate | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Glycerol | Thymidine | Corn starch | Gluconate Calcium | DL-Lysine |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Drug Repurposing Compound Library | Natural Product Library | Microbial Natural Product Library | FDA-Approved Drug Library | Natural Product Library for HTS | Cosmetic Ingredient Compound Library | Human Endogenous Metabolite Library | Bioactive Compounds Library Max | Gut Microbial Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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