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Postion:Product Catalog >Lactisole
Lactisole
  • Lactisole

Lactisole NEW

Price $29
Package 500mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: Lactisole CAS No.: 150436-68-3
Purity: 99.90% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameLactisole
DescriptionLactisole (na-PMP) is an inhibitor of the glucose-sensing receptor
In vitroIn MIN6 cells, in a dose-dependent manner, lactisole inhibited insulin secretion induced by sweeteners, acesulfame-K, sucralose and glycyrrhizin. The IC50 was ~4 mmol/l. Lactisole attenuated the elevation of cytoplasmic Ca2+ concentration ([Ca2+]c) evoked by sucralose and acesulfame-K but did not affect the elevation of intracellular cAMP concentration ([cAMP]c) induced by these sweeteners. Lactisole also inhibited the action of glucose in MIN6 cells. Thus, lactisole significantly reduced elevations of intracellular [NADH] and intracellular [ATP] induced by glucose, and also inhibited glucose-induced insulin secretion[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationEthanol : 1 mg/mL (4.58 mM), Sonication is recommended.
DMSO : 250 mg/mL (1145.84 mM), Sonication is recommended.
DMF : 20 mg/mL (91.67 mM), Sonication is recommended.
10% DMSO+90% Saline : 10 mg/mL (45.83 mM), Solution.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (9.17 mM), Sonication is recommended.
KeywordsTastereceptor | Taste receptor | Sweet taste receptor | Lactisole
Inhibitors RelatedDulcoside A | Neotame | Alitame hydrate | Denatonium benzoate | 6-Methoxyflavanone | FEMA 4774 | S6821 | Epiquinidine | Aspartame | Lysine-N,N-diacetic acid | Adenosine 5'-succinate | TAS2R14 agonist-2
Related Compound LibrariesBioactive Compound Library | ReFRAME Related Library | Food Additive Library | Drug Repurposing Compound Library | Inhibitor Library | Metabolism Compound Library | Clinical Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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