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Postion:Product Catalog >Linvencorvir
Linvencorvir
  • Linvencorvir

Linvencorvir NEW

Price $98 $263 $378
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-15

Product Details

Product Name: Linvencorvir CAS No.: 1808248-05-6
Purity: 99.90% Supply Ability: 10g
Release date: 2026/05/15

Product Introduction

Bioactivity

NameLinvencorvir
DescriptionLinvencorvir (RG7907) belongs to HBV core protein allosteric modulators (CpAM) and is an orally active HBV core protein inhibitor with potent anti-HBV activity, low CYP3A4 induction, and good metabolic stability. This compound is used for the treatment of chronic hepatitis B virus infection.
In vitroMethods: In HepG2.2.15 cells, treatment with different concentrations of Linvencorvir was performed to detect HBV DNA replication levels. Results: Linvencorvir inhibited HBV DNA replication with an EC50 of 62 nM. [1] Methods: In HepG2.117 cells, treatment with different concentrations of Linvencorvir was performed to detect HBV DNA production levels. Results: Linvencorvir inhibited HBV DNA production with an EC50 of 64 nM. [2]
In vivoMethods: In the AAV-HBV mouse model, oral administration of Linvencorvir (20 mg/kg, once daily) was given for 70 consecutive days, and serum and liver virological indicators as well as liver injury markers were detected. Results: Linvencorvir significantly reduced serum HBsAg, HBeAg, and liver AAV-HBV episome levels, induced hepatocyte apoptosis and proliferation, accompanied by transient ALT elevation.[2] Methods: In the AAV-HBV mouse model, oral administration of Linvencorvir (6-20 mg/kg, once daily) was given for 8 consecutive weeks, and serum HBV DNA, HBsAg, and HBeAg levels were detected. Results: Linvencorvir dose-dependently reduced serum HBV DNA, HBsAg, and HBeAg levels.[3]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 128.8 mg/mL (215.14 mM), Sonication is recommended.
KeywordsRG-7907 | RG 7907 | Linvencorvir | HBV | Antibiotic
Inhibitors RelatedNeomycin sulfate | Stavudine | Aceglutamide | Urea | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Lamivudine | Metronidazole | Doxycycline | Formamide | Alginic acid
Related Compound LibrariesBioactive Compound Library | Antibiotics Library | Anti-Viral Compound Library | Drug Repurposing Compound Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Infection Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Address: 36 Washington Street, Wellesley Hill, MA
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