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Postion:Product Catalog >Lipoxygenin
Lipoxygenin
  • Lipoxygenin

Lipoxygenin NEW

Price $159 $427 $775
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: Lipoxygenin CAS No.: 2247911-68-6
Supply Ability: 10g Release date: 2026/04/22

Product Introduction

Bioactivity

NameLipoxygenin
DescriptionLipoxygenin is an inhibitor of 5-lipoxygenase (5-LO) with an IC50value of 5 μM for inhibition of 5-LO product synthesis in isolated human granulocytes stimulated with the cation ionophore A23187 .1It inhibits hedgehog-dependent signaling in Shh-LIGHT2 cells and TGF-β-, activin A-, bone morphogenic protein (BMP)-, or Wnt-dependent signaling in HEK293T cells (IC50s = 9.3, 3.2, 8.2, 9.6, and 3.7 μM, respectively, in luciferase reporter assays). Lipoxygenin (5 and 10 μM) increases levels of troponin T (TnnT), a marker of cardiomyocyte differentiation, in human induced pluripotent stem cells (iPSCs) stimulated with BMP4 and the glycogen synthase kinase 3 (GSK3) inhibitor CHIR99021 .
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 30 mg/mL (74.55 mM), Sonication is recommended.
DMSO:PBS (pH 7.2) (1:1) : 0.5 mg/mL (1.24 mM), Sonication is recommended.
DMF : 30 mg/mL (74.55 mM), Sonication is recommended.
KeywordsLipoxygenin
Inhibitors Related2,5-Di-tert-butylhydroquinone | Caffeic Acid | 5-LOX inhibitor | 3-Aminobutanoic acid | Phenidone | 4-Aminosalicylic acid | Cuminaldehyde | NNK | Shogaol | Malotilate | 5-Aminosalicylic Acid | Tebufelone

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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