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Postion:Product Catalog >Biologics>Biochemical Reagents>Antagonist>Lotilaner
Lotilaner
  • Lotilaner
  • Lotilaner
  • Lotilaner
  • Lotilaner
  • Lotilaner

Lotilaner

Price $1
Package 1kg
Min. Order: 1kg
Supply Ability: 10000
Update Time: 2026-05-03

Product Details

Product Name: Lotilaner CAS No.: 1369852-71-0
Min. Order: 1kg Purity: 99%
Supply Ability: 10000 Release date: 2026/05/03

Article illustration

IUPAC Name:Lotilaner

Molecular Formula:C??H??Cl?F??N?O?

Molecular Weight:671.63 g/mol

CAS Number:1369852-71-0

Appearance:White to off-white crystalline powder

Solubility:Practically insoluble in water; soluble in organic solvents (e.g., DMSO, ethanol)

Melting Point:~150-155°C (decomposes)

pKa:~4.5 (weakly acidic)

Storage:2-8°C (protect from light and moisture)

Pharmacological Class:Isoxazoline-class ectoparasiticide

Mechanism of Action:GABA-gated chloride channel antagonist (selective for parasites)

Therapeutic Use:Veterinary medicine: Treatment and prevention of fleas and ticks in dogs and cats.

Brand Names:Credelio? (Elanco), Xzl? (Zoetis)

Regulatory Status:FDA/EMA-approved for veterinary use (oral administration).

Article illustration

ParameterSpecificationTest MethodTypical Result
Product NameLotilaner-Complies
CAS No.1369850-44-8-Complies
Batch No.(e.g., LT-20240701)-(Custom)
Manufacture DateYYYY-MM-DD-(Custom)
Expiry DateYYYY-MM-DD-(Custom)
AppearanceWhite to off-white powderVisual InspectionOff-white powder
Assay (HPLC)98.0%~102.0%HPLC (USP/EP)99.5%
Related Substances≤1.0% (total impurities)HPLC0.6%
Water Content (KF)≤0.5% w/wKarl Fischer0.3%
Residue on Ignition≤0.1%USP <281>0.05%
Heavy Metals≤10 ppm (as Pb)ICP-MS<5 ppm
Particle Size100% through 80 meshSieve AnalysisComplies
Microbial LimitsTAMC ≤1000 CFU/g, TYMC ≤100 CFU/gUSP <61>Complies
Residual SolventsMeOH ≤3000 ppm, EtOH ≤5000 ppmGC<2000 ppm (MeOH)
Optical Rotation[α]2?D = -10° to -15° (c=1 in DMF)Polarimetry-12.5°
Melting Point150~155°C (with decomposition)DSC152°C (dec.)

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Company Profile Introduction

HR Biotechnology Co., Ltd., located in East Lake high tech Development Zone, Wuhan, is a company specializing in the production and operation of chemical raw materials, flavors and fragrances, food additives, agrochemicals and other products. The company has first-class production equipment, advanced production technology, scientific management system, perfect detection means, and an excellent R & D team. The R & D center of the company has a technical team specialized in research and development, as well as a number of advanced detection, experiment and pilot equipment, and has established a good technical support relationship with a number of scientific research institutions, with strong technical force. The company has a wide range of products, in line with the quality of survival, service and development, customer-centric, integrity management philosophy, do our best to provide customers with quality and cheap raw materials. In addition, haorong also helps customers develop and implement customized system solutions. In these core areas of the chemical industry, haorong's core expertise covers chemicals and application technology, flexible asset management and customized services.

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