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Postion:Product Catalog >LR-90
LR-90
  • LR-90

LR-90 NEW

Price $37 $88 $148
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: LR-90 CAS No.: 245075-84-7
Purity: 99.68% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameLR-90
DescriptionLR-90, an advanced glycation end product (AGE) inhibitor, is utilized in diabetic animal model research. This compound effectively suppresses inflammatory responses in human monocytes.
In vitroLR-90 (0, 25, 50, 100, and 200 μM) significantly blocks THP-1 cell adherence to endothelial cells in a dose-dependent manner after 1-hour pretreatment followed by S100b stimulation for 24 hours, without affecting THP-1 cell viability. Additionally, LR-90 inhibits RAGE, MCP-1, COX-2, IP-10, and NOX2 mRNA expression in THP-1 cells dose-dependently after 1-hour pretreatment before S100b stimulation for 4 hours[1].
In vivoLR-90 (50 mg/L) decreases renal AGE, AGER and lipid peroxidation[2].LR-90 (50 mg/L, p.o. for 27 weeks) significantly reduces plasma lipids, modestly affects hyperglycaemia in ZDF rats[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (4.65 mM), Sonication is recommended.
DMSO : 95 mg/mL (133.88 mM), Sonication is recommended.
KeywordsLR-90 | LR90 | LR 90 | Inhibitor | inhibit | AGE
Inhibitors RelatedNaproxen sodium | Acetaminophen | Phenidone | 4-Aminosalicylic acid | Gallic Acid Monohydrate | Diclofenac Potassium | Indomethacin | Paradol | Trometamol | 5-Methylfurfural | Phenylbutazone | Magnesium sulfate
Related Compound LibrariesBioactive Compound Library | Neuronal Signaling Compound Library | Anti-Diabetic Compound Library | Inhibitor Library | NO PAINS Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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