LSD1-IN-25 NEW
| Price | Get Latest Price | |
| Package | 5mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: LSD1-IN-25 | CAS No.: 2911585-60-7 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | LSD1-IN-25 |
| Description | LSD1-IN-25 (Compound 9j) is a potent, selective, and orally active LSD1 inhibitor with an IC50 of 46 nM (Ki = 30.3 nM) that induces apoptosis in cancer cells [1]. |
| In vitro | LSD1-IN-25 (Compound 9j; 0-20 μM; 72 h) inhibits solid tumor cell proliferation [1] and, at 1-4 μM concentrations over 24 hours, increases H3K4me2 levels while inhibiting epithelial-mesenchymal transition (EMT) in H1650 cells [1]. Furthermore, LSD1-IN-25 (1-4 μM; 24 h) induces apoptosis and S-phase arrest in H1650 cells [1]. |
| In vivo | LSD1-IN-25 (Compound 9j; 10 and 20 mg/kg; oral gavage; daily for 21 days) demonstrated antitumor activity in an H1650 cell xenograft mouse model [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | HistoneDemethylase | Histone Demethylase |
| Inhibitors Related | Stavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | Dimethyl phthalate | Alginic acid | Sodium Molybdate | Sildenafil citrate |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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