M-110 NEW
| Price | $58 | $93 | Get Latest Price |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-14 |
Product Details
| Product Name: M-110 | CAS No.: 1395048-49-3 |
| Purity: 99.55% | Supply Ability: 10g |
| Release date: 2026/07/14 |
Product Introduction
Bioactivity
| Name | M-110 |
| Description | M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases, showing a preference for PIM-3 (IC50=47 nM), and inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 also inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM. |
| In vitro | M-110 has no activity on normal human peripheral blood mononuclear cells up to 40 μM. M-110 inhibits the expression of active STAT3 through inhibition of PIM-3. M-110 also inhibits the proliferation of 22Rv1, PC3, and SW480 cells, with IC50 values of 0.6 to 0.8 μM. M-110 (0.01-10 μM; 72 hours) inhibiting the growth of DU-145 cells (IC50: 0.9 μM). M-110 (10 μM; 18 hours) inhibits STAT3 Tyr705 phosphorylation[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (112.12 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.48 mM), Sonication is recommended. |
| Keywords | Pim3 | M-110 | M110 | M 110 |
| Inhibitors Related | Hispidulin | TCS-PIM-1-4a | SGI-1776 | CK2/ERK8-IN-1 | NSC756093 | Protein Kinase Inhibitor 12 | Pim-1 kinase inhibitor 4 | AZD1208 | Pim-1/2 kinase inhibitor 1 | Pim-1 kinase inhibitor 8 | TP-3654 | K00135 |
| Related Compound Libraries | Highly Selective Inhibitor Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Kinase Inhibitor Library | Hematonosis Compound Library | JAK-STAT Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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