m-PEG12-amine NEW
| Price | $40 | $56 | $81 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-20 |
Product Details
| Product Name: m-PEG12-amine | CAS No.: 1977493-48-3 |
| Purity: 99.92% | Supply Ability: 10g |
| Release date: 2026/05/20 |
Product Introduction
Bioactivity
| Name | m-PEG12-amine |
| Description | m-PEG12-amine is a PEG-based PROTAC linker and a non-cleavable 12-unit PEG ADC linker used in the synthesis of PROTACs [1] and antibody-drug conjugates (ADCs) [2]. |
| In vitro | PROTACs, or proteolysis-targeting chimeras, are composed of two distinct ligands joined by a linker. One of these ligands binds to a specific protein target, while the other binds to an E3 ubiquitin ligase. When the PROTAC binds to both the target protein and the E3 ligase, it triggers the ubiquitin-proteasome system within cells to degrade the target protein, thereby providing a mechanism for targeted protein degradation. |
| Storage | Store at low temperature,Keep away from direct sunlight Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 90 mg/mL (160.8 mM), Sonication is recommended. |
| Keywords | PROTAC Linkers | PEGs | Non-cleavable | m-PEG12-amine | m-PEG-12-amine | mPEG12amine | m PEG12 amine | ADCLinker | ADC linker |
| Inhibitors Related | Lenalidomide-Br | Boc-C16-COOH | N-(4-Carboxycyclohexylmethyl)maleimide | Azido-PEG1 | Succinic anhydride | Triethylene glycol | 11-Aminoundecanoic acid | 1,3-Dibromo-5,5-dimethylhydantoin | N-Hydroxysulfosuccinimide sodium | m-PEG12-NHS ester | Tetraethylene glycol | Tranexamic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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