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Postion:Product Catalog >MAPK-IN-1
MAPK-IN-1
  • MAPK-IN-1

MAPK-IN-1 NEW

Price $1520 $1980 $2500
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: MAPK-IN-1 CAS No.: 2470587-69-8
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

NameMAPK-IN-1
DescriptionMAPK-IN-1 (Compound 2) is an inhibitor of the MAPK signaling pathway with anti-neuroinflammatory and neuroprotective activities, suitable for Alzheimer's disease research. It inhibits AChE with an IC50 of 23.84 μM [1].
In vitroMAPK-IN-1 (Compound 2) effectively suppresses the release of pro-inflammatory mediators (NO, IL-1β, IL-6, and TNF-α) in BV-2 cells with IC50 values of 0.49 ± 0.17, 1.34 ± 0.21, 9.17 ± 0.17, and 8.17 ± 0.23 μM, respectively [1]. It also attenuates LPS-induced MAPK signaling pathway activation by inhibiting JNK, ERK, and p38 phosphorylation, and reduces expression of iNOS, COX-2, and TLR4 in LPS-stimulated BV-2 cells [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Inhibitors RelatedUndecane | Urea | Uridine 5'-monophosphate disodium salt | Gum arabic | Hydroxychloroquine | Fumaric acid | Benzyl alcohol | Lactose | D-Psicose | Dimethyl sulfoxide | Gluconate Calcium | Coumaran

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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