Product Details
| Product Name:
MBED |
CAS No.:
123363-40-6 |
| Supply Ability:
10g |
Release date:
2026/04/21 |
Product Introduction
Bioactivity
| Name | MBED |
| Description | MBED represents a highly specialized synthetic small molecule specifically engineered to modulate the calcium homeostasis within striated muscle fibers by acting as a potent allosteric enhancer of the ryanodine receptor type 1 channel while simultaneously exerting inhibitory effects on the sarcoplasmic reticulum calcium ATPase activity, effectively facilitating the measurable elevation of cytosolic calcium concentrations across various preclinical experimental models to evaluate the disruption of intracellular signaling during strictly monitored laboratory observation periods. |
| In vitro | In RyR1-expressing cell models and SR vesicles, MBED increased the open probability of RyR1 channels and inhibited SERCA1-mediated calcium sequestration with IC50 values of 10-30 uM [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | MBED |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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