Product Details
| Product Name:
McN3716 |
CAS No.:
69207-52-9 |
| Purity:
99.66% |
Supply Ability:
10g |
| Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | McN3716 |
| Description | McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor used for researching metabolic diseases. |
| In vivo | Significantly reducing the levels of all measured HETE and epoxytrienoic acids (EET), nonenzymatic auto-oxidative metabolites of ARA, by 23% to 44% and 32% to 50% compared with vehicle-injected rats, McN3716 (Methyl palmoxirate, MEP) achieves inhibition of brain mitochondrial β-oxidation. Notably, 15-HETE remains unaffected. McN3716 treatment leads to a significant 34% reduction in the level of 6-keto-PGF1α, a byproduct of PGI2 (prostacyclin). Similarly, the brain level of hydroxyeicosapentaenoic acids, nonenzymatic auto-oxidative metabolites of EPA, is reduced by 35% to 76% upon McN3716 treatment relative to the vehicle[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 2.99 mg/mL (10.02 mM), Sonication is recommended.
|
| Keywords | NSC-359682 | NSC 359682 | MitochondrialMetabolism | Mitochondrial Metabolism | McN-3716 | McN3716 | McN 3716 | CPT1 | Carnitine palmitoyltransferase I (CPT-1) |
| Inhibitors Related | Ciprofloxacin hydrochloride monohydrate | 1-Hexanol | Imeglimin hydrochloride | Rotenone | Glibenclamide | Permethrin | Ciprofloxacin monohydrochloride | (-)-Epigallocatechin Gallate | Phosphocreatine disodium | Sodium Molybdate | 4-Pentenoic acid | L-Histidine |
| Related Compound Libraries | Glycometabolism Compound Library | Bioactive Compound Library | ReFRAME Related Library | Multi-Target Compound Library | Inhibitor Library | Mitochondria-Targeted Compound Library | Metabolism Compound Library | Lipid Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Bioactive Lipid Compound Library | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$210.00
|
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-04-27 |
United States