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Postion:Product Catalog >Melagatran
Melagatran
  • Melagatran

Melagatran NEW

Price $540 $1260 $1630
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-06

Product Details

Product Name: Melagatran CAS No.: 159776-70-2
Purity: 99.83% Supply Ability: 10g
Release date: 2026/05/06

Product Introduction

Bioactivity

NameMelagatran
DescriptionMelagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin and does not significantly interact with any other enzymes in the coagulation cascade or with the fibrinolytic enzymes.
In vivoMETHODS: To test the hypothesis that a regimen consisting of an oral thrombin inhibitor would delay or prevent occlusive clot formation, anesthetized dogs were given melagatran (1.5, 2.5 mg/kg) via nasogastric tube, and 15 minutes later, a potent thrombogenic stimulus in the form of an anodic current (100 μA) was applied to the intimal surface of the stenotic left anterior descending coronary artery (LAD). RESULTS One of the dogs given high-dose melagatran did not develop thrombotic occlusion of the LAD during the entire 4-hour observation period. In the melagatran-treated dogs, coronary artery occlusions occurred during the observation period in 68% (low-dose) and 75% (high-dose) of the dogs.[2]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 45 mg/mL (104.77 mM), Sonication is recommended.
KeywordsThrombin | Melagatran
Inhibitors RelatedDabigatran Etexilate Mesylate | (S)-(+)-Ibuprofen | Edoxaban | AEBSF hydrochloride | Heparin sodium salt | Ozagrel | Avatrombopag | Dabigatran etexilate | Argatroban Monohydrate | Eltrombopag Olamine | Anisindione | p-Hydroxycinnamic acid
Related Compound LibrariesBioactive Compound Library | ReFRAME Related Library | Protease Inhibitor Library | Drug Repurposing Compound Library | Inhibitor Library | Orally Active Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Human Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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