Meropenem NEW
| Price | $42 | $58 |
| Package | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Meropenem | CAS No.: 96036-03-2 |
| Purity: 96.62% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Meropenem |
| Description | Meropenem (SM 7338) is a broad-spectrum carbapenem antibiotic administered intravenously for severe bacterial infections caused by sensitive agents. It commonly causes mild, transient aminotransferase elevations and can rarely lead to clinically apparent cholestatic liver injury. |
| Kinase Assay | Complementation of SCR7 Inhibition with Puri?ed Ligase IV: Complementation experiment is carried out by adding increasing concentrations of puri?ed Ligase IV/XRCC4 complex (30, 60, and 120 fmol) along with the oligomeric DNA substrates (5' compatible and 5'-5' noncompatible ends) to the SCR7-treatedextracts. Reactions are incubated for 2 h at 25℃. The reaction products are then resolved on 8% denaturing PAGE. The gel is dried and exposed and the signal is detected with a PhosphorImager and analyzed with Multi Gauge (V3.0) software. |
| In vitro | Meropenem significantly increases the urinary excretion of valproate-glucuronide in rabbits. |
| In vivo | Meropenem exhibits an antibacterial spectrum similar to that of imipenem, but demonstrates slightly lower activity against Staphylococcus aureus and Enterococcus. It possesses enhanced activity against Pseudomonas aeruginosa, all Enterobacteriaceae, and Haemophilus influenzae. Meropenem's antimicrobial efficacy against Gram-negative organisms is two to four times greater than that of imipenem, and it has a broader spectrum in comparison to all other tested agents. Furthermore, Meropenem exhibits an antagonistic effect when combined with several beta-lactam antibiotics against strain-producing type I cephalosporins. It binds most effectively to the penicillin-binding proteins 2 of Escherichia coli and Pseudomonas aeruginosa, and to the penicillin-binding protein 1 of Staphylococcus aureus. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 100 mg/mL (260.78 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) H2O : 5 mg/mL (13.04 mM), Sonication is recommended. |
| Keywords | β-lactamases | β-Lactamase | SM-7338 | SM7338 | parenteral | neutropenia | Meropenem | Inhibitor | inhibit | Gram-positive | Gram-negative | DHP-1 | D-alanyl-D-alanine carboxypeptidase DacB | carbapenem | Bacterial | Antibiotic | anaerobic |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Doxycycline (hyclate) | Kanamycin sulfate | Urethane | Sulfamethoxazole sodium | Doxycycline | EDTA copper(II) disodium salt | Isoeugenol | Dimethyl sulfoxide |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | Approved Drug Library | Pediatric Drug Library | EMA Approved Drug Library | Drug Repurposing Compound Library | Beta-Lactam Compound Library | Anti-Bacterial Compound Library | NO PAINS Compound Library | FDA-Approved Drug Library | Clinical Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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