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Postion:Product Catalog >Natural Products>Alkaloids>Mesaconine
Mesaconine
  • Mesaconine

Mesaconine NEW

Price $228
Package 1mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Mesaconine CAS No.: 6792-09-2
Purity: 98.00% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameMesaconine
DescriptionMesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and immune suppression.
In vitroThe anti-inflammatory effect of SFI was verified in vitro with endothelial cells. After detecting the cell viability, the expression of interleukin-6 (IL-6), inhibitor of nuclear factor kappa-B kinase (IKK), phosphorylated IKK, phosphorylated NF-κB and phosphorylated IκB-α± from the supernatant were determined. SFI could significantly suppress inflammatory responses, and the mechanism may be via an NF-κB-dependent pathway. Mesaconine is the first reported SFI compounds to have NF-κB inhibitor activity[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.12 mM), Sonication is recommended.
DMSO : 55 mg/mL (113.27 mM), Sonication is recommended.
KeywordsNF-κB | NFκB | NF-kB | NFkB | Mesaconine | Inhibitor | inhibit | Immunology & Inflammation related | ILReceptor | IL Receptor
Inhibitors RelatedUndecane | Sodium propionate | Ethyl palmitate | Kojic acid | Uridine | Fumaric acid | 1,4-Naphthoquinone | Glucosamine | Ethyl linoleate | D-Psicose | N,N-Dimethylacetamide | Magnesium sulfate
Related Compound LibrariesHIF-1 Signaling Pathway Compound Library | Tibetan medicine Compound Library | Ancient Chinese Classical Formulas Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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