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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Metabolism>Hydroxylase Inhibitors>Mildronate dihydrate
Mildronate dihydrate
  • Mildronate dihydrate

Mildronate dihydrate

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Package 1kg 1kg 1kg
Min. Order: 1kg
Supply Ability: 1T
Update Time: 2026-06-25

Product Details

Product Name: Mildronate dihydrate CAS No.: 86426-17-7
Min. Order: 1kg Purity: 99%
Supply Ability: 1T Release date: 2026/06/25
Product Name:Mildronate dihydrate
Synonyms:3-(2,2,2-Trimethylhydrazinium)propionate dihydrate;Mildronate dihydrate;Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt;Meldonium;Mildronate dihydrate, >=99%;Mildronate (hydrate);3-(1,1,1-Trimethylhydrazin-1-ium-2-yl)propanoate dihydrate;Meldonium dihydrate
CAS:86426-17-7
MF:C6H14N2O2.2H2O
MW:182.218
EINECS:695-494-3
Product Categories:Cardiovascular APIs;Inhibitors;86426-17-7
Mol File:86426-17-7.mol
Article illustration

Mildronate dihydrate Chemical Properties
Melting point 85 - 87°C
storage temp. 2-8°C
solubility H2O: >40mg/mL
form powder
color white to off-white
Water Solubility H2O: >40mg/mL
Stability:Hygroscopic
InChIKeyJFWLFLLRLZSBRA-UHFFFAOYSA-N

Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
MSDS Information

Mildronate dihydrate Usage And Synthesis
Appearancewhite to off-white powder
DescriptionMildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.Mildronate (40 μM) inhibits the reaction of γ-butyrobetaine hydroxylase with γ-butyrobetaine with Km and Vmax of 36.8 μM and 0.08 nmol/min/mg protein, respectively.
UsesMeldonium dihydrate has been used as an anti-ischemic agent to evaluate its protective effects on Ischemia-reperfusion (I/R) in chick embryos.
Biochem/physiol ActionsMeldonium is an Inhibitor of γ-butyrobetaine hydroxylase (BBOX) a key enzyme in the synthesis of carnitine.
in vivo

Meldonium (50, 100, or 200 mg/kg; once daily for 3 days) dihydrate modestly attenuates hypoxia-induced lung injury in mice[3].


Company Profile Introduction

Shandong Hanjiang Chemical Co., Ltd. is located in Zibo City, Shandong Province, China. It is a biotechnology enterprise engaged in the R&D, production and sales of drugs, steroids, peptides, raw materials, vitamins, food additives, animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. Advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, and its products are exported to countries all over the world. It has won a good international reputation for its excellent quality and excellent service. The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, and constantly strict requirements, Advantages: 1. Samples are provided for test; 2. Good quality products; 3. 100% secure delivery. 4. secure your money, lower the risk Payment ways: Western Union, Moneygram, Bitcoin, T/T Delivery: EMS/ EUB/ USPS/ UPS/ TNT/ FEDEX/ DHL etc Packaging:safe and discreet packaging Our company Superiority 1 Best service, high quality and reasonable price 2. It's customers' right to choose the package (EMS, DHL, FedEx, UPS); 3. It's customers' right to choose the packing way for his products from many recent effective packing ways 4. Specials are possible when client's order is big enough, including the discount policy; 5.Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time; Our company supply high quality chemical products with the most competitive prices. If have any need or question, contact us freely. Hope we can have chances to build good long-term cooperation.

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