Product Details
| Product Name:
MIV-247 |
CAS No.:
1352817-76-5 |
| Purity:
99.27% |
Supply Ability:
10g |
| Release date:
2026/05/23 |
Product Introduction
Bioactivity
| Name | MIV-247 |
| Description | MIV-247 is a selective and potent inhibitor of cathepsin S (Kis 2.1, 4.2, and 7.5 nM for human, mouse, and wild monkey cathepsin S, respectively), which attenuates mechanical anomalies in preclinical models of neuropathic pain, and can be used to study cardiac muscle injury. |
| In vivo | To assess the potential neurobehavioral side effects of MIV-247, oral administration of MIV-247 (100-200 μmol/kg) resulted in a dose-dependent reduction of mechanical allodynia, with up to approximately 50% reversal observed after single or twice-daily dosing for 5 days. No behavioral deficits were observed with any dose of MIV-247 tested[1]. |
| Storage | Store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Mouse Cathepsin S | MIV-247 | MIV247 | MIV 247 | Human Cathepsin S | CysteineProtease | Cysteine Protease | Cynomolgus monkey Cathepsin S | Cathepsin S |
| Inhibitors Related | Papain | 2-Aminoethanethiol | (S)-(+)-Ibuprofen | Asperphenamate | PMSF | JNJ-10311795 | N-Ethylmaleimide | Z-Lys-OH | Esomeprazole | 2-Cyanopyrimidine | Aloxistatin | 4-Methylesculetin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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