MMAF-OMe NEW
| Price | $34 | $52 | $82 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-22 |
Product Details
| Product Name: MMAF-OMe | CAS No.: 863971-12-4 |
| Purity: 99.34% | Supply Ability: 10g |
| Release date: 2026/04/22 |
Product Introduction
Bioactivity
| Name | MMAF-OMe |
| Description | MMAF-OMe (Monomethyl auristatin F methyl ester) is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively. MMAF-Ome is also an ADC cytotoxin. |
| In vitro | 2.5F-Fc and 2.5F-Fc-MMAF exhibit similar IC50 values (6.9±1.1 vs. 8.3±1.3 nM, respectively)[1], indicating that MMAF conjugation has a negligible impact on integrin-binding affinity[1]. |
| Storage | Powder: -20°C for 3 years Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 5% DMSO+95% Saline : 4 mg/mL (5.36 mM), Solution. DMSO : 99 mg/mL (132.71 mM), Sonication is recommended. |
| Keywords | MMAF-OMe | MMAFOMe | MMAF OMe | Inhibitor | inhibit | ADCCytotoxin | ADC Payload | ADC Cytotoxin |
| Inhibitors Related | Methotrexate | Mertansine | Doxorubicin hydrochloride | Exatecan | Methotrexate disodium | Camptothecin | Dexamethasone acetate | SN-38 | Dexamethasone | Fluticasone (propionate) | Paclitaxel | Exatecan Mesylate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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