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Postion:Product Catalog >Biochemical Engineering>Plant extracts>Plant Extracts>Mogroside III-E
Mogroside III-E
  • Mogroside III-E

Mogroside III-E NEW

Price $40 $98 $163
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: Mogroside III-E CAS No.: 88901-37-5
Purity: 99.85% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NameMogroside III-E
DescriptionMogroside III-E, a cucurbitane-type compound isolated from Siraitia grosvenorii, exhibits anti-inflammatory activity by attenuating LPS-induced acute lung injury in mice through the regulation of the TLR4/MAPK/NF-κB axis via AMPK activation. Additionally, it demonstrates anti-fibrotic activity by reducing pulmonary fibrosis through Toll-Like receptor 4 pathways.
In vitroMG IIIE elevated the cell viability of HG-induced MPC-5 cells, reduced the concentrations of inflammatory cytokines and decreased the levels of oxidative stress-related markers.?What's more, the apoptosis of podocytes induced by HG was inhibited after MG IIIE intervention, accompanied by the upregulated expression of Bcl-2 and downregulated expression of Bax, cleaved caspase-3 and cleaved caspase-9.?It was also found that MG IIIE could activate the AMPK/SIRT1 signaling, but compound C inhibited this pathway and reversed the inhibitory effects of MG IIIE on inflammation, oxidative stress and apoptosis in HG-stimulated podocytes.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (1.04 mM), Sonication is recommended.
DMSO : 9.64 mg/mL (10.01 mM), Sonication is recommended.
KeywordsTNF-α | TLR | Mogroside III-E | Mogroside IIIE | Mogroside III E | Inhibitor | inhibit | ILReceptor | IL Receptor
Inhibitors RelatedKaolin | Fluorene | Undecane | Ethyl palmitate | Gum arabic | Hydroxychloroquine | Benzyl alcohol | 1,8-Cineole | Dodecane | 1,4-Naphthoquinone | Tributyrin | Glucosamine
Related Compound LibrariesAnti-Tumor Natural Product Library | Terpene Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Saccharide and Glycoside Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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