Product Details
| Product Name:
MRL-871 |
CAS No.:
1392809-08-3 |
| Purity:
99.66% |
Supply Ability:
10g |
| Release date:
2026/04/20 |
Product Introduction
Bioactivity
| Name | MRL-871 |
| Description | MRL-871 is a selective RORγt allosteric inhibitor, reducing IL-17a mRNA production in EL4 cells, interacting with PPARgamma in partial agonistic binding modes. |
| In vitro | MRL-871 is a reverse agonist of retinoic acid-associated orphan receptor γt (RORγt) with a high affinity, KD value of 250 nM and IC50 of 264 nM. [1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 15 mg/mL (33.72 mM), Sonication is recommended.
|
| Inhibitors Related | S18-000003 | T0901317 | GSK2981278 | GSK805 | Nobiletin | XY101 | AZD-0284 | Melatonin | SR2211 | SR 1903 | Cholesterol | ML 209 |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Post-Translational Modification Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Suppliers |
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Shaoxing Anpai Import & Export Co. Ltd
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2021-07-07 |
United States