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Postion:Product Catalog >MRT-81
MRT-81
  • MRT-81

MRT-81 NEW

Price $59 $89 $161
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-05-16

Product Details

Product Name: MRT-81 CAS No.: 1263132-08-6
Purity: 99.72% Supply Ability: 10g
Release date: 2026/05/16

Product Introduction

Bioactivity

NameMRT-81
DescriptionMRT-81 is a potent antagonist of human and rodent smoothened receptors that inhibits hedgehog activity with an IC50 value of 41 nM in Shh-light2 cells.It is used in the study of cancer.
In vitroMRT-81 inhibits the differentiation of the mesenchymal pluripotent C3H10T1/2 cells into alkaline phosphatase positive osteoblasts induced by the Smo agonist SAG with 0.1 μM, with an IC50 value of 64 nM[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 50 mg/mL (89.99 mM), Sonication is recommended.
10% DMSO+90% Corn Oil : 2.5 mg/mL (4.5 mM), Sonication is recommended.
KeywordsSmoothened | Smo | Shh-light2 cells | rodent | rat granule cell precursors | MRT-81 | MRT81 | MRT 81 | Inhibitor | inhibit | human | Hedgehog | C3H10T1/2 cells | BODIPY-cyclopamine
Inhibitors RelatedItraconazole | Naftifine hydrochloride | IHR-1 | GANT 61 | ALLO-2 | 5-LOX inhibitor | Ellagic acid | Triparanol | Vismodegib | Halcinonide | MRT-83 | RU-SKI 43
Related Compound LibrariesOsteogenesis Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Hematonosis Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library | Wnt/Hedgehog/Notch Compound Library | Anti-Cancer Active Compound Library | Neuronal Differentiation Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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