Product Details
| Product Name:
MRTX0902 |
CAS No.:
2654743-22-1 |
| Purity:
99.69% |
Supply Ability:
10g |
| Release date:
2026/04/20 |
Product Introduction
Bioactivity
| Name | MRTX0902 |
| Description | MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 nM and a Ki of 2 nM. |
| In vitro | In the MIA PaCa-2 xenograft model of mice, MRTX0902 (25 and 50 mg/kg; p.o.) shows anti-tumor effects and reduces tumor growth by 41% and 53%, respectively[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 10 mg/mL (25.74 mM), Sonication and heating to 60℃ are recommended.
10% DMSO+90% Saline : 1 mg/mL (2.57 mM), Sonication is recommended.
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| Keywords | SOS1 | MRTX-0902 | MRTX0902 | MRTX 0902 |
| Inhibitors Related | Adagrasib | Regorafenib monohydrate | RMC-9805 | Vemurafenib | Sorafenib | (R)-Naproxen | Ketoconazole | MRTX1133 | Regorafenib | Dabrafenib | Sotorasib | Daraxonrasib |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library | MAPK Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Price |
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Suppliers |
Update time |
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Hubei Chuchang Biotech Co., Ltd.
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2025-03-16 |
United States