Product Details
| Product Name:
MV151 |
CAS No.:
945611-88-1 |
| Purity:
100.00% |
Supply Ability:
10g |
| Release date:
2026/05/15 |
Product Introduction
Bioactivity
| Name | MV151 |
| Description | MV151 is a fluorescent dye and a proteasome inhibitor with cell permeability, capable of specifically targeting all active subunits of proteasomes and immunoproteasomes in living cells. Used for in vitro and in vivo proteasome labeling and functional studies. |
| In vitro | Methods: In EL-4 and HeLa cell lysates, MV151 was incubated at concentrations from 10 nM to 10 μM for 1 hour, followed by proteasome labeling and gel detection.
Results: MV151 uniformly labeled all active subunits (β1, β2, β5), with detection possible at 10 nM and saturation at 1 μM, showing sensitivity more than 3-fold higher than silver staining.[1] |
| In vivo | Methods: In C57Bl/6 and UbG76V-GFP transgenic mice, a single intraperitoneal injection of MV151 (20 μmol/kg, solvent 60% DMSO/40% PBS) was administered, and detection was performed 24 h later.
Results: Significant fluorescent labeling was observed in the liver and pancreas, consistent with GFP reporter accumulation, confirming that MV151 effectively labels and inhibits the proteasome in vivo.[1] |
| Storage | Keep away from direct sunlight,Keep away from moisture,Store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | MV-151 | MV151 | Bodipy TMRAhx(3)L(3)VS. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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