Product Details
| Product Name:
MY10 |
CAS No.:
2204270-73-3 |
| Purity:
98.64% |
Supply Ability:
10g |
| Release date:
2026/05/26 |
Product Introduction
Bioactivity
| Name | MY10 |
| Description | MY10, a potent and orally active inhibitor of the receptor protein tyrosine phosphatase (RPTPβ/ζ), effectively reduces binge-like ethanol consumption and diminishes the rewarding effects of ethanol. |
| In vivo | MY10 (20, 60, 100 mg/kg; oral gavage; 3 days; rat) reduced alcohol consumption in the alcohol operant self-administration paradigm (p = 0.040). In the DID-MSA paradigm, rats drank significantly less alcohol (p = 0.019) and showed a significant decrease in alcohol preference (p = 0.002). We observed that the longer the exposure to alcohol, the greater the suppressing effects of MY10 on alcohol consumption. It was demonstrated that the effects of MY10 were specific to alcohol since saccharin intake was not affected by MY10 (p = 0.804). MY10 prevented the alcohol-induced down-regulation of Ptprz1 (p = 0.004) and anaplastic lymphoma kinase (Alk; p = 0.013) expression.[2] |
| Storage | Keep away from direct sunlight,Store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 45 mg/mL (117.08 mM), Sonication is recommended.
|
| Keywords | protein tyrosine phosphatase(PTP) |
| Inhibitors Related | Sodium propionate | Ethyl palmitate | Kojic acid | Uridine | Decanoic Acid | Fumaric acid | 1,4-Naphthoquinone | Glucosamine | Ethyl linoleate | D-Psicose | N,N-Dimethylacetamide | Magnesium sulfate |
| Related Compound Libraries | NF-κB Signaling Compound Library | Glycometabolism Compound Library | Bioactive Compound Library | Tyrosine Kinase Inhibitor Library | Inhibitor Library | Metabolism Compound Library | Orally Active Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Phosphatase Inhibitor Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Price |
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Suppliers |
Update time |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States