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Postion:Product Catalog >Naproxcinod
Naproxcinod
  • Naproxcinod

Naproxcinod NEW

Price $1520 $1980 $2500
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Naproxcinod CAS No.: 163133-43-5
Purity: 99.85% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameNaproxcinod
DescriptionNaproxcinod is a derivative of naproxen exhibiting analgesic and anti-inflammatory activity. As a cyclooxygenase (COX)-inhibitory nitric oxide donor (CINOD), it is indicated for osteoarthritis and inflammatory conditions.
In vitroNaproxcinod (1-30 μM, 15 minutes) increased cGMP levels in a concentration-dependent manner, reaching up to 27 times the baseline level [1]. Naproxcinod (1-100 μM, 8 hours) enhanced HO-1 mRNA expression in endothelial cells in a concentration-dependent manner [2].
In vivoNaproxcinod (0, 10, 21, and 41 mg/kg, orally administered once daily for 42 weeks) significantly increased average body weight (+7.3%) compared to the solvent control group and improved skeletal and cardiac disease phenotypes in DMD mice [3].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsNaproxen-N-butyl Nitrate | Naproxcinod | HCT 3012 | AZD-3582
Inhibitors Related2-Isopropyl-1H-imidazole | Acetaminophen | Phenidone | Aminopicoline | Gallic Acid Monohydrate | Indomethacin | Methylene Blue trihydrate | Paradol | Trometamol | Gluconate Calcium | 5-Methylfurfural | Magnesium sulfate
Related Compound LibrariesBioactive Compound Library | Neuronal Signaling Compound Library | Drug Repurposing Compound Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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