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Postion:Product Catalog >NCT-502
NCT-502
  • NCT-502

NCT-502 NEW

Price $52 $79 $162
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: NCT-502 CAS No.: 1542213-00-2
Purity: 99.60% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameNCT-502
DescriptionNCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.
In vitroNCT-502 is cytotoxic to MDA-MB-468 (EC50: 15.2 μM)[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.06 mM), Sonication is recommended.
H2O : < 0.1 mg/mL (insoluble)
DMSO : 55 mg/mL (139.08 mM), Sonication is recommended.
KeywordsPHGDH | NCT-502 | NCT502 | NCT 502 | Inhibitor | inhibit
Inhibitors RelatedDisulfiram | Mycophenolate Mofetil | Rotenone | Ribavirin | 18β-Glycyrrhetinic acid | Benzyl alcohol | 2-Methylaminoethanol | Methotrexate disodium | Dimethyl malonate | Isomalt | D-Mannitol | Ethyl potassium malonate
Related Compound LibrariesBioactive Compound Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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