NIAD-4 NEW
| Price | $30 | $68 | Get Latest Price |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: NIAD-4 | CAS No.: 868592-56-7 |
| Purity: 99.66% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | NIAD-4 |
| Description | NIAD-4 is a near-infrared (NIR) fluorescent label targeting amyloid-beta (Ki=10 nM) capable of crossing the blood-brain barrier. It serves as a fluorophore for optical imaging of Aβ in the central nervous system (CNS) for Alzheimer's disease, with absorption peaks at 475–480 nm. |
| In vitro | NIAD-4 can enhance fluorescence quantum yield and fluorescence intensity by binding to amyloid aggregates and hindering their internal rotation, making it an effective tool for detecting amyloid proteins. Due to its charge neutrality and low molecular weight, NIAD-4 can penetrate the blood-brain barrier and can be used for imaging amyloid fibrils in the brain. The excitation wavelength of NIAD-4 is 475 nM, and the emission wavelength is 610 nM [2][3]. |
| Storage | Keep away from direct sunlight Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 0.2 mg/mL (0.6 mM), Sonication is recommended. DMSO : 20 mg/mL (59.81 mM), Sonication is recommended. DMSO:PBS(pH 7.2) (1:2) : 0.3 mg/mL (0.9 mM), Sonication is recommended. DMF : 25 mg/mL (74.76 mM), Sonication is recommended. |
| Keywords | NIAD-4 | NIAD 4 |
| Inhibitors Related | Benzenesulfonamide | Deferoxamine Mesylate | Cromolyn sodium | HEPPS | Phytic acid sodium salt | Rutin | 10-Undecenoic acid | Pyridoxal phosphate | 2,4-Di-tert-butylphenol | Chlorzoxazone | Methyl tridecanoate | Glimepiride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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