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Postion:Product Catalog >API>Digestive system drugs>Antacid and Mucosal protective Drugs>Nizatidine
Nizatidine
  • Nizatidine

Nizatidine NEW

Price $29
Package 1mL
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Nizatidine CAS No.: 76963-41-2
Purity: 98.39% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameNizatidine
DescriptionNizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity.
In vitroIn rats, Nizatidine exhibits its maximum inhibitory effect on gastric acid secretion one hour after administration, with an EC50 value of 1.383 μMol/kg. Intravenous administration of Nizatidine (0.3-3 mg/kg) not only enhances gastrointestinal motility but also suppresses gastric acid secretion, achieving 50% of the maximal effect at a dose of 2.94 mg/kg and 90% at 19.6 mg/kg for rats.
In vivoNizatidine is a reversible, non-competitive inhibitor of acetylcholinesterase (IC50=6.7 μM, Ki=7.4 μM) and a selective antagonist of the histamine H2 receptor, effectively inhibiting gastric acid secretion (IC50=0.9 nM).
StorageKeep away from direct sunlight,Store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 60 mg/mL (181.02 mM), Sonication is recommended.
H2O : 26 mg/mL (78.44 mM), Sonication is recommended.
Ethanol : 15 mg/mL (45.25 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (9.96 mM), Sonication is recommended.
Keywordsstomach | Nizatidine | intestines ulcers | Inhibitor | inhibit | HistamineReceptor | Histamine Receptor | hcc | H2 receptor | GERD | gastroesophageal reflux disease | erosive esophagitis | cancer | acid | AChE
Inhibitors RelatedUndecane | Uridine 5'-monophosphate disodium salt | Meclizine dihydrochloride | Ethyl (triphenylphosphoranylidene) acetate | Famotidine | Diethyltoluamide | Sodium butanoate | Dimethyl sulfoxide | Coumaran | Alginic acid | Methyl tridecanoate | Trimethylammonium chloride
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Orally Active Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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