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Postion:Product Catalog >NMS-859
NMS-859
  • NMS-859

NMS-859 NEW

Price $97 $136 $198
Package 1mg 2mg 5mg
Supply Ability: 10g
Update Time: 2026-05-25

Product Details

Product Name: NMS-859 CAS No.: 1449236-96-7
Purity: 98.20% Supply Ability: 10g
Release date: 2026/05/25

Product Introduction

Bioactivity

NameNMS-859
DescriptionNMS-859 is an effective and covalent inhibitor of valosin-containing protein (VCP)/p97 with IC50s of 0.37 μM and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.
In vitroNMS-859 suppresses the cell proliferation with IC50s of 3.0 μM and 3.5 μM in HeLa and HCT116 cell lines, respectively. NMS-859 shows weak inhibitory activity against VCPC522T[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 3.5 mg/mL (10.01 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.86 mM), Sonication is recommended.
KeywordsZINC-169324353 | ZINC 169324353 | valosin-containing protein (VCP)/p97 | NMS-859 | NMS859 | NMS 859
Inhibitors RelatedDBEQ | CB-5339 | MSC1094308 | UP12 | ML241 hydrochloride | NMS-873 | NPD8733 | NSC799462 | MNS | Eeyarestatin I | ML240 | CB-5083
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Covalent Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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