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Postion:Product Catalog >API>Circulatory system drugs>Anti Shock vasoactive drugs>Norepinephrine
Norepinephrine
  • Norepinephrine

Norepinephrine NEW

Price $41
Package 100mg
Supply Ability: 10g
Update Time: 2026-04-20

Product Details

Product Name: Norepinephrine CAS No.: 51-41-2
Purity: 99.90% Supply Ability: 10g
Release date: 2026/04/20

Product Introduction

Bioactivity

NameNorepinephrine
DescriptionNorepinephrine is an alkaloid neurotransmitter and an effective adrenergic receptor (AR) agonist that activates α1, α2, and β1 receptors. It is commonly used as a vasoactive agent for the treatment of shock and can also be used to induce cardiomyopathy models.
In vitroMETHODS: Adult hippocampal cells were treated with Norepinephrine (0.1-10 μM) for 10-13 days and the number of neurospheres was determined using classical neurosphere assay. RESULTS: A significant increase in the number of neurospheres was obtained at 100 nm and in the presence of 1 μM Norepinephrine, and a twofold increase in the number of neurospheres was observed in the presence of 10 μM Norepinephrine. [1] METHODS: Human pancreatic cancer cells BxPC-3 and Panc-1 were treated with Norepinephrine (10 μM) for 12-48 h. Cell viability was assayed by MTT Assay. RESULTS: Norepinephrine treatment alone significantly enhanced the viability of PDAC cells. [2]
In vivoMETHODS: To test in vivo activity, Norepinephrine (0.2-2 mg/kga) was administered intraperitoneally to C57BL6/J mice fed a high-fat diet once daily for two weeks. RESULTS: A subset of Norepinephrine-treated mice developed unexpected adverse events, including bladder dilatation and decreased renal perfusion due to renal discoloration. [3]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information0.1M HCl : 10 mg/mL (59.11 mM), Sonication is recommended.
H2O : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 8.46 mg/mL (50.01 mM), Sonication and heating are recommended.
10% DMSO+90% Saline : 0.1 mg/mL (0.59 mM), Solution.
Keywordsβ1-adrenoceptor | α2A-adrenoceptor | α1-adrenoceptor | Norepinephrine | MMP-9 | MMP-2 | Levarterenol | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | Beta Receptor | Autophagy | AdrenergicReceptor | Adrenergic Receptor
Inhibitors RelatedSucrose | Aceglutamide | Hemin | Nicotinamide riboside malate | DL-Lysine | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Glycerol | Thymidine | Corn starch | Gluconate Calcium
Related Compound LibrariesAnti-Tumor Natural Product Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Miao medicine Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Human Endogenous Metabolite Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | GPCR Compound Library | Food as Medicine Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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