NP-1815-PX NEW
| Price | $1520 |
| Package | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-16 |
Product Details
| Product Name: NP-1815-PX | CAS No.: 1239578-80-3 |
| Purity: 99.39% | Supply Ability: 10g |
| Release date: 2026/04/16 |
Product Introduction
Bioactivity
| Name | NP-1815-PX |
| Description | NP-1815-PX is a selective P2X4 receptor antagonist with anti-inflammatory and analgesic properties. It inhibits guinea pig tracheal/bronchial smooth muscle contraction and can be used to study chronic pain. |
| In vitro | NP-1815-PX is a novel selective antagonist of P2X4R. NP-1815-PX effectively inhibited the increase of [Ca2+]i in P2x4R-mediated HP2x4R-1321N1 cells in a concentration-dependent manner, with IC50 value of 0.26 μM for hP2X4R. [1] |
| In vivo | In a mouse model of chronic pain, NP-1815-PX inhibited mechanical abnormal pain induced by nerve damage without any change in basal pain sensitivity or motor function. NP-1815-PX showed inhibitory effect on mechanical abnormal pain in a herpes pain model. [1] |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | P2XReceptor | P2X Receptor | NP-1815-PX | Neladenoson dalanate | Neladenoson bialanate. | BAY10-67197 | BAY-10-67197 | BAY1067197 | BAY-106,7197 | BAY106,7197 | BAY 10-67197 | BAY 1067197 | BAY 106,7197 |
| Inhibitors Related | Gefapixant citrate | Eperisone hydrochloride | Aurintricarboxylic acid | Sodium metatungstate | (E/Z)-Sivopixant | PSB-12062 | ATP disodium salt | Oxatomide | JNJ-42253432 | Ivermectin | Lappaconitine | Paroxetine |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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