NS3694 NEW
| Price | $31 | $44 | $72 |
| Package | 1mg | 2mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: NS3694 | CAS No.: 426834-38-0 |
| Purity: 99.92% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | NS3694 |
| Description | NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation. |
| In vitro | NS3694 (10, 50, and 100 μM) specifically inhibits cytochrome c- and dATP-induced DEVDase activation and processing of caspases and caspase substrates, thus inhibiting the mitochondria-mediated apoptosis. NS3694 inhibits the formation of the apoptosome Apaf-1 by blocking the activation of the initiator caspase-9. In MCF-casp3 cells, NS3694 (10-100 μM) inhibits dose-dependently caspase 9, 3, and 7 processing, DFF45/ICAD, and PARP cleavage, and DEVDase activity and inhibits TNF-induced effector caspase activation and apoptosis[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 250 mg/mL (696.96 mM), Sonication is recommended. 10% DMSO+90% Saline : < 10 mg/mL (27.88 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (27.88 mM), Suspension. |
| Keywords | NS-3694 | NS3694 | NS 3694 | Inhibitor | inhibit | cytochrome c | caspase-9 | apoptosome inhibitor | Apoptosis | Apaf-1 |
| Inhibitors Related | Stavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | Dimethyl phthalate | Alginic acid | Sodium Molybdate | Sildenafil citrate |
| Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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VIP2Y
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Shaanxi Dideu New Materials Co. Ltd
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2026-06-27 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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