一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
+1 (818) 612-2111
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >NSC781406
NSC781406
  • NSC781406

NSC781406 NEW

Price $58 $94 $171
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: NSC781406 CAS No.: 1676893-24-5
Purity: 99.58% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NameNSC781406
DescriptionNSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).
In vitroNSC781406 shows reasonable liver microsome stability. NSC781406 displays effective PI3K inhibition (PI3Kα IC50=2.0 nM) that translates into BEL-7404 cells proliferation inhibition (IC50=20 nM) and it also demonstrates cytotoxic activities against leukemia, non-small cell, lung cancer, colon cancer, central nervous system cancer, melanoma, ovarian cancer, renal cancer, prostate cancer, and breast cancer. It is effective against 60 cancer cell lines with a mean GI50 value of 65 nM and with a GI50 value of less than 10 nM against four cancer cell lines.
In vivoNSC781406 is well tolerated at 30 mg/kg, with no observed mortality or significant reduction of body weight. NSC781406(30 mg/kg) treatment, causes statistically significant antitumor activity, in the xenograft models. It has a mean reduction in the relative tumor volume ratio of 52%. Sorafenib shows an inhibition ratio of 44% at 50 mg/kg .
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 150 mg/mL (238.98 mM), Sonication is recommended.
10% DMSO+90% Corn Oil : 4 mg/mL (6.37 mM), Sonication is recommended.
KeywordsPI3Kδ | PI3Kγ | PI3Kβ | PI3Kα | PI3K | Phosphoinositide 3-kinase | NSC-781406 | NSC781406 | NSC 781406 | mTOR | Mammalian target of Rapamycin | Inhibitor | inhibit
Inhibitors RelatedMusk ketone | Stearamide | L-Leucine | Myricetin | Creatine monohydrate | Hyaluronic acid | L-Proline | Isoprenaline hydrochloride | Metformin | Methyl eugenol | Quercetin | Dihydromyricetin
Related Compound LibrariesAnti-Lung Cancer Compound Library | Glycometabolism Compound Library | Bioactive Compound Library | Antidepressant Compound Library | Kinase Inhibitor Library | Inhibitor Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Oxidation-Reduction Compound Library | Neuronal Differentiation Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
Anhui Ruihan Technology Co., Ltd
2023-08-21

TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY
静乐县| 富顺县| 凤台县| 洱源县| 扶风县| 陆丰市| 鄂托克旗| 漳浦县| 皋兰县| 神农架林区| 宁都县| 南投县| 宁国市| 达孜县| 黑河市| 松潘县| 沧州市| 上杭县| 平乐县| 维西| 龙南县| 通化市| 十堰市| 贵阳市| 额敏县| 迁安市| 克什克腾旗| 南阳市| 西安市| 静乐县| 色达县| 泾川县| 轮台县| 霸州市| 山阴县| 高阳县| 邯郸县| 峨边| 民勤县| 剑阁县| 浦北县|